Spravato® (Esketamine)

How Spravato Works

Spravato® (esketamine) is a prescription nasal spray that works differently from traditional antidepressants. While most medications for depression take weeks to start working, Spravato targets a different part of the brain and can bring relief much faster—sometimes within hours or days.

Spravato helps your brain form new connections that improve mood, thinking, and emotional balance. It’s especially helpful for people who haven’t felt better after trying two or more antidepressants. During your visit, you’ll spray the medicine in your nose while being supervised by a medical professional. Afterward, you’ll relax in a comfortable setting for about two hours while we monitor how you’re feeling.

This treatment can be a life-changing option for those struggling with treatment-resistant depression or depression with suicidal thoughts. When combined with an oral antidepressant, Spravato offers hope for people who haven’t found relief with other treatments.

What to Expect During Treatment

Patients self-administer Spravato at our clinic under the direct supervision of a licensed medical provider. Each session includes pre- and post-monitoring to ensure safety and comfort, typically lasting around two hours. Spravato is administered twice weekly during the initial phase and gradually tapers as progress is made. Most patients receive treatment over the course of several weeks as part of a personalized care plan.

Is Spravato Right for You?

Spravato may be appropriate if you’ve tried two or more oral antidepressants without success, you experience persistent depressive symptoms or you’ve had thoughts of self-harm or suicidal ideation in the context of MDD

Our team will conduct a comprehensive evaluation to determine if Spravato is the right option for your needs.

Take Back Your Life Today.

Call us at (216) 383 – 2834 to schedule a Spravato Consultation and learn if Spravato is right for you.